Genetic Evidence That a Gut Commensal Bacterium Can Cause Colorectal Cancer

نویسندگان

چکیده

SUMMARY Our gastrointestinal tract is colonized by trillions of microbes. There growing recognition that commensal bacteria can promote the development colorectal adenomas and cancer. For example, bacterial plaques are strongly associated with in familial adenomatous polyposis (Science 2018;359:592-597), fusobacterium cancer liver metastasis.(Science 2017;358:1443-1448)

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Gut Microbiota and Colorectal Cancer.

BACKGROUND Colorectal cancer (CRC) is a leading cause of cancer-related mortality worldwide whose incidence has increased rapidly in recent years. There is growing evidence that the complex gut microbiota community plays an important role in the development of intestinal tumorigenesis. SUMMARY This review aimed to explore the correlation between gut microbiota and CRC as well as to identify t...

متن کامل

Polymorphism and Genetic Diversity of BAT25 Marker in Colorectal Cancer

By its frequency, colorectal cancer (CRC) has become a serious public health problem. BAT25 marker is included in the panel of five markers dedicated to the diagnosis of CCR microsatellite instability. The objective of this study was to evaluate the polymorphism and genetic diversity of the BAT25 marker in CRC cases in Senegal. This prospective study was performed on 22 CRC patients. After DNA ...

متن کامل

Can tattoos cause cancer?

Myth: Tattooing has risen in popularity, but can this body art increase the risk of cancer? Answer: Tattoos and body piercings have been prevalent for thousands of years in many cultures. Tattooed mummies from Egypt, Peru, and the Philippines have been radiocarbon dated to 2000 BC. The word tattoo is derived from the Tahitian word ta-tau, which means “the result of tapping.” Modern artists use ...

متن کامل

Gut microbiota, epigenetic modification and colorectal cancer

Micro-organisms contain 90% of cells in human body and trillions foreign genes versus less than 30 thousand of their own. The human colon host various species of microorganisms, appraised at more than 1014 microbiota and contained of over a thousand species. Although each one's profile is separable, the relative abundance and distribution of bacterial species is the same between healthy ones, c...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Gastroenterology

سال: 2021

ISSN: ['1528-0012', '0016-5085']

DOI: https://doi.org/10.1053/j.gastro.2020.12.014